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Chronic diseases impose a sustained burden on healthcare systems through progressive deterioration and long-term costs. Although adherence-enhancing interventions are widely promoted, their return on investment (ROI) remains uncertain, particularly under heterogeneous patient behavior and socioeconomic variation.
Simulations indicate that timing and design of chronic care policies matter significantly—programs that start early and adapt over time outperform delayed or costly low-impact interventions, helping policymakers target resources more effectively.
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Undernutrition and reduced health-related quality of life (HRQoL) are common in severe chronic obstructive pulmonary disease (COPD) and may exacerbate functional decline. This study evaluated whether …
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