Personalizing a Weight Loss Program Using Cognitive-Behavioral Phenotypes to Improve Engagement and Weight Loss in Adults With Overweight or Obesity

Personalizing a Weight Loss Program Using Cognitive-Behavioral Phenotypes to Improve Engagement and Weight Loss in Adults With Overweight or Obesity

Obesity affects more than one-quarter of adults in the United Kingdom and is a leading cause of preventable disease and health care costs. Digital behavior change programs can provide scalable weight management support, but maintaining engagement is challenging, and engagement is strongly associated with weight loss success. Tailoring interventions to cognitive-behavioral phenotypes, distinct patterns of thinking and behavior, offers one strategy to improve adherence. Although such approaches show promise in controlled settings, evidence from real-world digital programs is limited.
 

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A stand-alone digital intervention designed to increase physical activity among office workers showed promising usability and moderate engagement, suggesting digital tools can support workplace health behavior change. However, sustained participation remains a challenge, highlighting the need for more engaging and personalized content to maintain long-term activity improvements.


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